Iranian Joual of Public Health 2016. 45(10):1322-1331. Can Opium Use Contribute to a Higher Risk of Colorectal Cancers? A Matched Case-control Study in Iran Ahmad NAGHIBZADEH-TAHAMI, Vahid YAZDI FEYZABADI, Narges KHANJANI, Ahad ASHRAFI-ASGARABAD, Hosniyeh ALIZAEH, Vahid Reza BORHANINEJAD, Mohammad MORADI-JOO, Masoud ZEINALI, Mohammad Javad ZAHEDI, Mahmoud AGHAEE-AFSHAR, Ali Akbar HAGHDOOST Abstract Background: Colorectal cancers (CRCs) including colon, rectum and anal cancers are the third most prevalent cancers in the world. There are strong evidence showing the risk of the cigarette smoking, alcohol use, low physical activity and some types of diets in CRCs; however, few studies explored the relationship between opium use and CRCs. This study aimed to investigate the association between opioid use and the incidence of CRCs. Methods: In a population-based matched case-control study in Kerman, Iran, 175 patients with colorectal cancers and 350 healthy controls (matched for age, se

Metformin Versus Sulfonylurea in Breast Cancer Risk of Diabetic Patients: A Systematic Review and Meta-Analysis Mohammad Moradi-Joo , Sahar Mohabbat-Bahar , Saeed Heidari , Sayed Hossein Davoodi , Sepideh Gareh Sheyklo and Mohammad-Esmaeil Akbari Abstract Context: Metformin has been used for diabetic patients. This medicine might decrease the risk of breast cancer. The main objective of this article was to determine the breast cancer risk in diabetic patients and its association with metformin and sulfonylurea. Evidence Acquisition: In order to gather evidences, main databases [MEDLINE, PubMed, Cochrane library, Science Direct, Trip, Google Scholar, Institute of Scientific Information (ISI), SCOPUS and EMBASE] as well as relevant websites have searched without time limitation up to June 2015. We have searched with appropriate keywords and strategies. After quality assessment of studies, consequences of risk and mortality for breast cancer have extracted. RevMan and co